10/23 〜 12/22 の輪読

ブログ更新をしばらくサボりました．とりあえず，この間に輪読で取り上げた論文の紹介です．

1236. Corral, M.G. et al. (2017). Exploiting the evolutionary relationship between malarial parasites and plants to develop new herbicides. Angew. Chem. Int. Ed. 56: 9881–9885.

1237. Inoue, Y. et al. (2017). Evolution of the wheat blast fungus through functional losses in a host specificity determinant. Science 357: 80–83.

1238. Minden, V., Deloy, A., Volkert, A.M., Leonhardt, S.D., and Pufal, G. (2017). Antibiotics impact plant traits, even at small concentrations. AoB PLANTS 9: plx010.

1239. Yokoyama, C., Takei, M., Kouzuma, Y., Nagata, S., and Suzuki, Y. (2017). Novel tryptophan metabolic pathways in auxin biosynthesis in silkworm. J. Insect Physiol. 101: 91–96.

1240. Du, M. et al. (2017). MYC2 orchestrates a hierarchical transcriptional cascade that regulates jasmonate-mediated plant immunity in tomato. Plant Cell 29: 1883–1906.

1241. Wu, J. et al. (2017). Synergy of synthesis, computation and NMR reveals correct baulamycin structures. Nature 547: 436–440.

1242. Miwa, A. et al. (2017). Nicotinamide mononucleotide and related metabolites induce disease resistance against fungal phytopathogens in Arabidopsis and barley. Sci. Rep. 7: 6389.

1243. Farrell, K., Jahan, A.M., and Kovinich, N. (2017). Distinct mechanisms of biotic and chemical elicitors enable additive elicitation of the anticancer phytoalexin glyceollin I. Molecules 22: 1261.

1244. Ueno, Y. et al. (2017). WRKY45 phosphorylation at threonine 266 acts negatively on WRKY45-dependent blast resistance in rice. Plant Signaling Behav. 12: e1356968.

1245. Cheval, C. et al. (2017). PRR2, a pseudo-response regulator, promotes salicylic acid and camalexin accumulation during plant immunity. Sci. Rep. 7: 6979.

1246. Baccelli, I., Glauser, G., and Mauch-Mani, B. (2017). The accumulation of β-aminobutyric acid is controlled by the plant’s immune system. Planta 246: 791–796.

1247. Mageroy, M.H. et al. (2017). A conifer UDP-sugar dependent glycosyltransferase contributes to acetophenone metabolism and defense against insects. Plant Physiol. 175: 641–651.

1248. Lee, K., Choi, G.-H., and Back, K. (2017). Cadmium-induced melatonin synthesis in rice requires light, hydrogen peroxide, and nitric oxide: key regulatory roles for tryptophan decarboxylase and caffeic acid O-methyltransferase. J. Pineal Res. 63: e12441.

1249. Zahid, A. et al. (2017). Holaphyllamine, a steroid, is able to induce defense responses in Arabidopsis thaliana and increases resistance against bacterial infection. Planta 246: 1109–1124.

1250. Hatsugai, N. et al. (2017). A plant effector-triggered immunity signaling sector is inhibited by pattern-triggered immunity. The EMBO Journal 36: 2661–2807.

1251. Tjiurutue, M.C., Sandler, H.A., Kersch-Becker, M.F., Theis, N., and Adler, L.S. (2017). Gypsy moth herbivory induced volatiles and reduced parasite attachment to cranberry hosts. Oecologia 185: 133–145.

1252. Pedras, S.M., Abdoli, A., and Sarma-Mamillapalle, K.V. (2017). Inhibitors of the detoxifying enzyme of the phytoalexin brassinin based on quinoline and isoquinoline scaffolds. Molecules 22: 1345.

1253. Zhang, Y. et al. (2017). The Magnaporthe oryzae Alt A 1-like protein MoHrip1 binds to the plant plasma membrane. Biochem. Biophys. Res. Commun. 492: 55–60.

1254. Ma, Z., Ongena, M., and Höfte, M. (2017). The cyclic lipopeptide orfamide induces systemic resistance in rice to Cochliobolus miyabeanus but not to Magnaporthe oryzae. Plant Cell Rep. 36: 1731–1746.

1255. Williams, I.S. et al. (2017). Biotransformation of chrysin to baicalein: selective c6-hydroxylation of 5,7-dihydroxyflavone using whole yeast cells stably expressing human CYP1A1 enzyme. J. Agric. Food Chem. 65: 7440–7446.

1256. Biała, W., Banasiak, J., Jarzyniak, K., Pawela, A., and Jasi≈Ñski, M. (2017). Medicago truncatula ABCG10 is a transporter of 4-coumarate and liquiritigenin in the medicarpin biosynthetic pathway. J. Exp. Bot. 68: 3231–3241.

1257. Erice, G., Ru√≠z-Lozano, J.M., Zamarre√±o, √.Å.M., Garc√≠a-Mina, J.M., and Aroca, R. (2017). Transcriptomic analysis reveals the importance of JA-Ile turnover in the response of Arabidopsis plants to plant growth promoting rhizobacteria and salinity. Environ. Exp. Bot. 143: 10–19.

1258. Ignea, C. et al. (2017). Overcoming the plasticity of plant specialized metabolism for selective diterpene production in yeast. Sci. Rep. 7: 8855.

1259. Yun, C.-S., Motoyama, T., and Osada, H. (2017). Regulatory mechanism of mycotoxin tenuazonic acid production in Pyricularia oryzae. ACS Chem. Biol. 12: 2270–2274.

1260. Yoshida, Y. et al. (2017). OsTGAP1 is responsible for JA-inducible diterpenoid phytoalexin biosynthesis in rice roots with biological impacts on allelopathic interaction. Physiol. Plant. 161: 532–544.

1261. Abe, I., Mitsuhashi, T., and Okada, M. (2017). Identification of chimeric αβγ diterpene synthases possessing both type ΙΙ terpene cyclase and prenyltransferase activities. ChemBioChem 18: 2104–2109.

1262. Chezem, W.R., Memon, A., Li, F.-S., Weng, J.-K., and Clay, N.K. (2017). SG2-type R2R3-MYB transcription factor MYB15 controls defense-induced lignification and basal immunity in Arabidopsis. Plant Cell 29: 1907–1926.

1263. Jiang, C.-J. et al. (2017). Stunted growth caused by blast disease in rice seedlings is associated with changes in phytohormone signaling pathways. Front. Plant Sci. 8: 1558.

今週の輪読

今週の輪読では下記の論文を取り上げました．

1232. Zhu, Q. et al. (2017). FRET-based glucose imaging identifies glucose signalling in response to biotic and abiotic stresses in rice roots. J. Plant Physiol. 215: 65–72.

1233. Chakravarthy, S., Worley, J.N., Montes-Rodriguez, A., and Collmer, A. Pseudomonas syringae pv. tomato DC3000 polymutants deploying coronatine and two type III effectors produce quantifiable chlorotic spots from individual bacterial colonies in Nicotiana benthamiana leaves. Mol. Plant Pathol. in press.

1234. Jeong, J.S., Jung, C., Seo, J.S., Kim, J.-K., and Chua, N.-H. (2017). The deubiquitinating enzymes UBP12 and UBP13 positively regulate MYC2 levels in jasmonate responses. Plant Cell 29: 1406–1424.

1235. Wang, J. et al. (2017). OsBSK1-2, an orthologous of atbsk1, is involved in rice immunity. Front. Plant Sci. 8: 908.

今週の輪読

今週は都合により輪読が 2 回しかできませんでしたが，下記の論文を取り上げました．

1230. Valdameri, G. et al. (2017). Herbaspirillum rubrisubalbicans, a mild pathogen impairs growth of rice by augmenting ethylene levels. Plant Mol. Biol. 94: 625–640.

1231. Kalaivani, K., Kalaiselvi, M.M., and Senthil-Nathan, S. Effect of methyl salicylate (MeSA) induced changes in rice plant (Oryza sativa) that affect growth and development of the rice leaffolder, Cnaphalocrocis medinalis. Physiol. Mol. Plant Pathol. in press.

今週の輪読

後期は火曜日は長谷川が 12:40 から授業なので，12:30 からの輪読は基本的に休みになりました．また，今週木曜日は長谷川が品川で開催されたブルカーの NMR ユーザーズミーティングに出席したので，輪読は休みでした．

今週の輪読では下記の論文を取り上げました．

1227. Shirai, T. et al. (2017). Identification of a novel TRPM8 agonist from nutmeg: a promising cooling compound. ACS Med. Chem. Lett. 8: 715–719.

1228. Zhang, J. et al. (2017). Silencing OsSLR1 enhances the resistance of rice to the brown planthopper Nilaparvata lugens. Plant Cell Environ. 40: 2147–2159.

1229. Martínez-Medina, A., Van Wees, S.C.M., and Pieterse, C.M.J. Airborne signals by Trichoderma fungi stimulate iron uptake responses in roots resulting in priming of jasmonic acid-dependent defences in shoots of Arabidopsis thaliana and Solanum lycopersicum. Plant Cell Environ. in press.

新学期 & 今週の輪読

今年度は後期の開始が早くなり，9/28 から授業が開始しました．

今週の輪読では下記の論文を取り上げました．

1222. Li, Y. et al. RESISTANCE TO POWDERY MILDEW8.1 boosts pattern-triggered immunity against multiple pathogens in Arabidopsis and rice. Plant Biotechnol. J. in press.

1223. Khare, D. et al. (2017). Arabidopsis ABCG34 contributes to defense against necrotrophic pathogens by mediating the secretion of camalexin. Proc. Natl. Acad. Sci. USA 114: E5715–E5720.

1224. Adebesin, F. et al. (2017). Emission of volatile organic compounds from petunia flowers is facilitated by an ABC transporter. Science 356: 1386–1388.

1225. Woodcock, B.A. et al. (2017). Country-specific effects of neonicotinoid pesticides on honey bees and wild bees. Science 356: 1393–1395.

1226. Tsvetkov, N. et al. (2017). Chronic exposure to neonicotinoids reduces honey bee health near corn crops. Science 356: 1395–1397.

今週の輪読

今週の輪読では下記の論文を取り上げました．

1218. Machado, R.A.R., Baldwin, I.T., and Erb, M. (2017). Herbivory-induced jasmonates constrain plant sugar accumulation and growth by antagonizing gibberellin signaling and not by promoting secondary metabolite production. New Phytol. 215: 803–812.

1219. Lee, H.-A., Kim, S., Kim, S., and Choi, D. (2017). Expansion of sesquiterpene biosynthetic gene clusters in pepper confers nonhost resistance to the Irish potato famine pathogen. New Phytol. 215: 1132–1143.

1220. Selim, S., Sanssen√©, J., Rossard, S., and Courtois, J. (2017). Systemic induction of the defensin and phytoalexin pisatin pathways in pea (Pisum sativum) against Aphanomyces euteiches by acetylated and nonacetylated oligogalacturonides. Molecules 22: 1017.

1221. Samota, M.K. et al. (2017). Elicitor-induced biochemical and molecular manifestations to improve drought tolerance in rice (Oryza sativa L.) through seed-priming. Front. Plant Sci. 8: 934.

研究室旅行 & 9/12〜14 の輪読

9/15（金）には生物制御化学研究室と化学生態学研究室合同で稲敷市のこもれび森のイバライド（旧ポティロンの森）へ日帰り旅行に行きました．イバライドでは芝滑り，キャンドル作り，バーベキュー，動物への餌やりやふれあい，ゴーカート，ロングジップスライドなどで一日遊びました．

芝滑りに興じる学生たち

ロングジップスライドで滑空する鈴木教授（左）と戸嶋教授（右）

長谷川の製作した水分子キャンドル

（学生たちはもっとマシなものを作っていましたが，写真がないです）

9/12〜14 の輪読では下記の論文を取り上げました．

1215. Luginbuehl, L.H. et al. (2017). Fatty acids in arbuscular mycorrhizal fungi are synthesized by the host plant. Science 356: 1175–1178.

1216. Jiang, Y. et al. (2017). Plants transfer lipids to sustain colonization by mutualistic mycorrhizal and parasitic fungi. Science 356: 1172–1175.

1217. Saini, S.S. et al. (2017). Benzaldehyde dehydrogenase-driven phytoalexin biosynthesis in elicitor-treated Pyrus pyrifolia cell cultures. J. Plant Physiol. 215: 154–162.

今週の輪読

今週の輪読では下記の論文を取り上げました．

1210. Liang, X., Chen, X., Li, C., Fan, J., and Guo, Z. (2017). Metabolic and transcriptional alternations for defense by interfering OsWRKY62 and OsWRKY76 transcriptions in rice. Sci. Rep. 7: 2474.

1211. Pedras, M.S.C., and Abdoli, A. (2017). Pathogen inactivation of cruciferous phytoalexins: detoxification reactions, enzymes and inhibitors. RSC Adv. 7: 23633–23646.

1212. Pawełek, A., Duszyn, M., Świeżawska, B., Szmidt-Jaworska, A., and Jaworski, K. (2017). Transcriptional response of a novel HpCDPK1 kinase gene from Hippeastrum x hybr. to wounding and fungal infection. J. Plant Physiol. 216: 108–117.

1213. Świeżawska, B., Jaworski, K., Duszyn, M., Pawełek, A., and Szmidt-Jaworska, A. (2017). The Hippeastrum hybridum PepR1 gene (HpPepR1) encodes a functional guanylyl cyclase and is involved in early response to fungal infection. J. Plant Physiol. 216: 100–107.

1214. Katz, E., and Chamovitz, D.A. (2017). Wounding of Arabidopsis leaves induces indole-3-carbinol-dependent autophagy in roots of Arabidopsis thaliana. Plant J. 91: 779–787.

停電，8/28 〜 9/1 の輪読

9/2（土）は年に一度の電気設備点検のための停電がありました．停電の時には常時稼働している NMR や質量分析計などを停止しなければいけません．今回は停止ついでに LC/MS/MS のメンテナンスも実施しました．停電後の再起動も特に問題なく，各機器とも週明けから順調に使えているようです．

8/28 〜 9/1 の輪読では下記の論文を取り上げました．

1205. Yang, X.-F., Kong, C.-H., Yang, X., and Li, Y.-F. Interference of allelopathic rice with penoxsulam-resistant barnyardgrass. Pest Manage. Sci. in press.

1206. Riedlmeier, M. et al. (2017). Monoterpenes support systemic acquired resistance within and between plants. Plant Cell 29/6: 1440–1459.

1207. Berasategui, A. et al. (2017). Gut microbiota of the pine weevil degrades conifer diterpenes and increases insect fitness. Mol. Ecol. 26: 4099–4110.

1208. Becker, L. et al. (2017). Correlative analysis of fluorescent phytoalexins by mass spectrometry imaging and fluorescence microscopy in grapevine leaves. Anal. Chem. 89: 7099–7106.

1209. Li, D. et al. (2017). Quantification of near-attomole gibberellins in floral organs dissected from a single Arabidopsis thaliana flower. Plant J. 91: 547–557.

いわき秀英高校模擬授業，大学院入試，今週の輪読

8/21 は長谷川は福島県いわき市にあるいわき秀英高校で「はじめての農薬学」というタイトルで模擬授業を実施しました．いわき秀英高校は常磐線泉駅から徒歩で 20 分ぐらいのところにある私立高校ですが，校舎が立派なビルでびっくりしました．教室には Apple TV に接続された電子黒板が用意されていて，iPad Pro を AirPlay ミラーリングで接続してプレゼンテーションができるようになっていました．大学では，未だに VGA ケーブルでプロジェクタに接続しているので，羨ましい限りです．

8/26 には茨城大学大学院農学研究科の入学試験が実施されました．今年度から大学院入試にも推薦入試が導入されて，推薦入試の方は 5 月に行われました．こちらは一般入試です．

今週の輪読では下記の論文を取り上げました．

1201. Takeshita, N. et al. (2017). Pulses of Ca²⁺ coordinate actin assembly and exocytosis for stepwise cell extension. Proc. Natl. Acad. Sci. USA 114: 5701–5706.

1202. Ueda, M. et al. (2017). Noncanonical function of a small-molecular virulence factor coronatine against plant immunity: an in vivo Raman imaging approach. ACS Central Science 3: 462–472.

1203. Kanda, Y. et al. (2017). The receptor-like cytoplasmic kinase BSR1 mediates chitin-induced defense signaling in rice cells. Biosci. Biotechnol. Biochem. 81: 1497–1502.

1204. Ube, N. et al. (2017). Evolutionary changes in defensive specialized metabolism in the genus Hordeum. Phytochemistry 141: 1–10.

夏休み & 8/7〜18 の輪読

しばらく前から大学のカリキュラムでは授業回数（15 回 + 試験 1 回）の確保が重要視されてきています．さらに最近，それに加えてクォーター制という一年を 4 分割するシステムが導入されました．こういった関係で夏休みを従来より短くするしかなくなり，今年度から茨城大学では 8/12〜9/20 が夏季休業期間です．研究室は概ね通常通り営業中ですが，8/11〜16 の間は全学一斉休業でしたので，研究室もお休みでした．

8/7〜18 の輪読では下記の論文を取り上げました．

1196. Kyndt, T. et al. (2017). Below-ground attack by the root knot nematode Meloidogyne graminicola predisposes rice to blast disease. Mol. Plant Microbe Interact. 30: 255–266.

1197. Hacham, Y., Matityahu, I., and Amir, R. (2017). Transgenic tobacco plants having a higher level of methionine are more sensitive to oxidative stress. Physiol. Plant. 160: 242–252.

1198. Park, S.-I. et al. (2017). Improved stress tolerance and productivity in transgenic rice plants constitutively expressing the Oryza sativa glutathione synthetase OsGS under paddy field conditions. J. Plant Physiol. 215: 39–47.

1199. Xu, G. et al. (2017). Global translational reprogramming is a fundamental layer of immune regulation in plants. Nature 545: 487–490.

1200. Xu, G. et al. (2017). uORF-mediated translation allows engineered plant disease resistance without fitness costs. Nature 545: 491–494.

研究室セミナー & 今週の輪読

今週の研究室セミナーでは 4 年生の周君が下記の論文を紹介しました．

Chen, J., Xie, Y., Chen, J., and Zhang, H. (2015). Asymmetric total synthesis of (–)-stenine. Tetrahedron 71: 3747–3755.

今週の輪読では下記の論文を取り上げました．

1192. Spallek, T. et al. (2017). Interspecies hormonal control of host root morphology by parasitic plants. Proc. Natl. Acad. Sci. USA 114: 5283–5288.

1193. Hartmann, M. et al. (2017). Biochemical principles and functional aspects of pipecolic acid biosynthesis in plant immunity. Plant Physiol. 174: 124–153.

1194. Schimmel, B.C.J. et al. (2017). Overcompensation of herbivore reproduction through hyper-suppression of plant defenses in response to competition. New Phytol. 214: 1688–1701.

1195. Perri, D., Gorosito, N., Fernandez, P., and Buteler, M. (2017). Plant-based compounds with potential as push-pull stimuli to manage behavior of leaf-cutting ants. Entomol. Exp. Appl. 163: 150–159.

農学部オープンキャンパス

7/22 は水戸キャンパスで茨城大学全学のオープンキャンパスが開催されましたが，昨日は阿見キャンパスで農学部オープンキャンパスが開催されました．農学部オープンキャンパスでは農学部の各研究室が高校生の見学のために公開されます．生物制御化学研究室は 1 階のあまり人通りが多くない場所にあるので，いつもあまり見学者が多くない傾向にあるのですが，今年は例年よりも見学者が多かった印象でした．後で聞いたところによると，千名以上の来場者があったそうです．これは例年に比べるとかなり多い数です．

研究室セミナー & 今週の輪読

今週の研究室セミナーでは 4 年生の香川君が下記の論文を紹介しました．

Mao, Y.-B. et al. (2017). Jasmonate response decay and defense metabolite accumulation contributes to age-regulated dynamics of plant insect resistance. Nat. Commun. 8: 13925.

今週の輪読では下記の論文を取り上げました．

1187. Xie, Y. et al. (2017). Digital gene expression profiling of the pathogen-resistance mechanism of Oryza sativa 9311 in response to Bacillus amyloliquefaciens FZB42 induction. Biol. Control 110: 89–97.

1188. Ma, D. et al. (2017). Overexpression of a type-I isopentenyl pyrophosphate isomerase of Artemisia annua in the cytosol leads to high arteannuin B production and artemisinin increase. Plant J. 91: 466–479.

1189. Zhou, K. et al. (2017). Bioactivity and structure-activity relationship of cinnamic acid esters and their derivatives as potential antifungal agents for plant protection. PLOS ONE 12: e0176189.

1190. Zhang, X., Abrahan, C., Colquhoun, T.A., and Liu, C.-J. (2017). A proteolytic regulator controlling chalcone synthase stability and flavonoid biosynthesis in Arabidopsis. Plant Cell 29: 1157–1174.

1191. Corbin, C. et al. (2017). Functional characterization of the pinoresinol–lariciresinol reductase-2 gene reveals its roles in yatein biosynthesis and flax defense response. Planta in press.